REF 48. Principles of QSAR, AOP and read-across

Alternative methods in regulatory toxicology

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Aimed at

Manufacturers/importers of substances/mixtures, downstream users including formulators and distributors, and end-users of substances/mixtures.

Objectives

  • The aim of this module is to provide an introduction to the concepts of (Q)SAR, read-across and chemical category. Participants will learn about the scientific basis of (Q)SAR models, their scope and limitations. The most commonly used models will also be presented with practical examples, and common errors in their use will be reviewed.

Contents

1. Introduction

  • Concept of (Q)SAR and its evolution
  • The concept of chemical category
  • Application criteria

    • 2. Most commonly used models

  • Physico-chemical
  • Toxicological
  • Ecotoxicological

    • 3. Strengths and weaknesses

  • Scope of application
  • OECD validation criteria
  • Use in regulatory affairs
  • Documentation required by ECHA

    • 4. AOP (Adverse Outcome Pathways)

  • Concept
  • AOP wiki

    • Course details

    • Duration: 3 hours
    • Date: 2 July 2026
    • Time: 10:00 to 13:00
    • Venue: Virtual Classroom

    Cost

    • Per person: €450 + VAT
    • Subsidised course: €411 + VAT (approx.)

    Interested in this course?

    For registration or additional information, please send an email to fedequim@fedequim.es or contact Fedequim through fedequim.es/contacto